Benign prostatic hyperplasia and prostatic carcinoma are the most frequent and important two lesions of the prostate. Sometimes we encounter the situations ot solve the problems for the differential of cancerous lesions form various
histopathologic
changes in the microscopic examination of the prostate tissue obtained by curettage or resection in the patients of benign prostatic hyperplasia. This study was undertaken to make an accurate histopathologic diagnosis of the prostate through the
recognition of various microscopic changes similar to those of prostatic cancer and to understand the possibility of precancerous lesion in the dysplasia of the prostate.
Authors reviewed total 1,023 cases of prostatic tissue obtained during the last ten years form 1981 to 1990 at Ewha Womans University Tongdaemun Hospital, wonju Christian Hospital and Yong-Dong Severance Hospital.
@ES The results are as follows:
@EN 1) Among total 1,023 cases, 922 cases were benign prostatic hyperplasia and 101 cases were prostatic carcinoma.
2) Dominant age groups are seventies are seventies and eighties decades.
3) Nonspecific inflammation is found in almost cases of benign prostatic hyperplasia and the incidence of granulomatous inflammation was 2.7%, that of nonspecific granulomatous inflammation was 1.8% and that of tuberculosis was 1.0%.
4) The incidence of stromal nodule in benign prostatic hyperplasia was 30.5%, basal cell hyperplasia, 29.7%, sclerosing adenosis, 2.1% land dysplasia, 3.5%%.
5) Among total 983 cases of prostate, 54 cases(5.5%) were dysplasia. The incidence of dysplasia in benign prostatic hyperplasia was 3.9% and that in prostatic carcinoma was 29.5%. The incidence of grade III dyplasia was 0.3% in benign prostatic
hyperplasia and 13.1% in prostatic carcinoma. Therefore, dysplasia can be considered as the premalignant lesion of the prostate and the possibility of presence and occurance of associated carcinoma in the grade III dysplasia is highly present.
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